2016-10-05

SwePub titelinformation: Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan

Objective To determine the association between changes in the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) index over 2 years as a measure of cartilage proteoglycan concentration, with changes in cartilage thickness in the medial tibiofemoral compartment of knees in middle-aged women. Methods One hundred and forty-eight women (one knee for each subject) aged ≥40 years were included low dGEMRIC index in the repair tissue two years postoperatively indicated fibrocartilage of low quality. A negative correlation between the dGEMRIC index and future OA suggested that the quality of the surrounding cartilage influences the outcome after cartilage repair surgery. Background: Even though cartilage loss is a known feature of psoriatic (PsA) and rheumatoid arthritis (RA), research is sparse on its role in the pathogenesis of PsA, its potential use for disease monitoring and for differentiation from RA. We therefore assessed the use of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) to evaluate biochemical cartilage changes in BACKGROUND: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a validated technique for evaluating cartilage health in developmental dysplasia of the hip (DDH), which can be a helpful prognosticator for the response to surgical treatments. dGEMRIC requires intravenous injection of gadolinium contrast, however, which adds time, expense, and possible adverse reactions to the imaging The dGEMRIC technique can be easily implemented clinically by using a standard 1.5 or 3.0 T magnet. Although the duration of the total acquisition time (up to 2 hours) diminishes its attractiveness for clinical use, dGEMRIC has potential value in clinical trials, where it has shown the ability to demonstrate changes in morphologically intact cartilage that may be predictive of progression to OBJECTIVE: Our aim was to investigate the relation between radiograph-based subchondral bone structure and cartilage composition assessed with delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC) and T2 relaxation time. Delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) Following ACL Injury.

Dgemric

Brosket liksom Magnevist är negativt laddade och repellerar varandra. Magnevist givet intravenöst tas därför Kan dGEMRIC diagnosticera tidig artros? I vetenskapliga studier, där andra frågeställningar än rent kliniska kan vara relevanta har ytterligare for traumatic cartilage injuries remains unknown. Contrast-enhanced MRI of cartilage (dGEMRIC) evaluates cartilage quality and a low dGEMRIC index may… av EM Roos · Citerat av 8 — Tiderius CJ, Olsson LE, Leander P, Ekberg O, Dahlberg L. Delayed gadolinium- enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis. Magn Reson.

Materials and Methods.

SwePub titelinformation: Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan

Reference values of healthy‐appearing cartilage from all individuals and values in areas of chondromalacia were assessed The dGEMRIC index and indentation stiffness were highly correlated within regions, within cartilage from the same joint, and across cartilage from all the joints, so long as the dGEMRIC index from with dGEMRIC for the detection of cartilage damage? Do the mean acetabular and femoral dGEMRIC indices differ between (2) superior acetabular clock positions with and without impingement and (3)between cam andpincer FAI? METHODS We performed a retrospective, institutional review board– approved, comparative radiological study of 21 hips in 20 Background: Even though cartilage loss is a known feature of psoriatic (PsA) and rheumatoid arthritis (RA), research is sparse on its role in the pathogenesis of PsA, its potential use for disease monitoring and for differentiation from RA. We therefore assessed the use of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) to evaluate biochemical cartilage changes in The dGEMRIC technique can be easily implemented clinically by using a standard 1.5 or 3.0 T magnet. Although the duration of the total acquisition time (up to 2 hours) diminishes its attractiveness for clinical use, dGEMRIC has potential value in clinical trials, where it has shown the ability to demonstrate changes in morphologically intact In another prospective, randomized, placebo-controlled, double-blind pilot trial on patients with mild knee osteoarthritis, taking 10 grams of collagen supplement with type 2 collagen and proteoglycans for 6 months led to positive changes in cartilage tissue using the delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC

Apr 2, 2016 The dGEMRIC scan shows fairly extensive acetabular cartilage damage as indicated by dark red and black regions in the acetabular cartilage.

Delayed contrast-enhanced MRI of cartilage (dGEMRIC) is a noninvasive technique to study cartilage glycosaminoglycan (GAG) content in vivo. This study evaluates dGEMRIC in patients with preradiographic degenerative cartilage changes. Seventeen knees in 15 patients (age 35-70) with arthroscopically v …. Delayed contrast-enhanced MRI of cartilage 2013-07-01 Background: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a validated technique for evaluating cartilage health in developmental dysplasia of the hip (DDH), which can be a helpful prognosticator for the response to surgical treatments.

dGEMRIC procedure [3], anionic gadolinium contrast agent (Gd-DTPA 2− ) is first injected intravenously or intraarticularly and then allowed to diffuse into the cartilage during a pre- All Acronyms, dGEMRIC (Feb. 17, 2021, 6:02 AM), available at https://www.allacronyms.com/DGEMRIC. CSE All Acronyms. dGEMRIC [Internet]; February 17, 2021 [cited 2021 FEB 17]. Human studies evaluating dGEMRIC as a prognostic tool for knee osteoarthritis Owman, Henrik LU In Lund University Faculty of Medicine Doctoral Dissertation Series 2014:22.
Parrelationer bok

dGEMRIC av höftledsbrosk. Långtidseffekt av träning • 37 friska försökspersoner (medelålder 25 år). med hjälp av tredimensionell kontrastförstärkt 145 000 magnetkameraundersökning (3D dGEMRIC) Vilken betydelse har lokalt producerade signalsubstanser För att bedöma brosket på MR, användes förutom morfologisk information dGEMRIC T1- och T2-kartor, som ger information om dess vatten- och nopausal women. Magnus Tveit Exercise in youth and long-term effects on bone and joints. Zana Hawezi Sub-regional dGEMRIC analysis and contrast distri-.

Average T1 for Four Slices Patient T1 (ms) Control T1 (ms) No. Sex/Age Anterior Posterior Sex/Age Anterior Posterior The objective of the study are: Evaluate OA progression by evaluating cartilage morphology, cartilage glycosaminoglycan (GAG) content, and joint space changes measured by MRI (3.0T), dGEMRIC index, and radiography, respectively using age-matched control subjects to identify disease related changes.
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Delayed gadolinium-enhanced. MRI of cartilage (dGEMRIC) is a previously presented method for identification of early OA using magnetic resonance imaging

Decreasing physical activity leads to a decrease in GAG content in the cartilage. Variation in cartilage thickness is a source of error in dGEMRIC studies that should be considered. Imaging of Cartilage (dGEMRIC) technique is a well-established method for early assessment of cartilage quality in osteoarthritis [1]. Using this technique, the distribution of Gd-(DTPA)2− contrast agent in cartilage after intravenous injection is assessed with quantitative T 1 mapping.